Preclinical Studies

MORRIS PLAINS, N.J., Aug. 18, 2016 (GLOBE NEWSWIRE) — Immunomedics, Inc. (Nasdaq:IMMU) today announced that adding an inhibitor of ATP-binding cassette (ABC) transporters to sacituzumab govitecan, the Company’s lead antibody-drug conjugate (ADC) for solid cancer therapy, increased the median survival of mice bearing a SN-38-resistant human gastric cancer cell line. Results from this preclinical study […]

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A military medical research institute has announced that it plans to move ahead with human testing for a potential Zika vaccine by the end of this year after getting two positive results with laboratory mice. Results from the preclinical study, led by the Walter Reed Army Institute of Research, were published this week in Nature. […]

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IRVINE, Calif., Aug. 02, 2016 (GLOBE NEWSWIRE) — Endologix, Inc. (NASDAQ:ELGX), developer and marketer of innovative treatments for aortic disorders, today announced financial results for the three and six months ended June 30, 2016. John McDermott, Endologix Chairman and Chief Executive Officer, said, “We continue to deliver solid revenue growth above expectations and are very […]

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Alzheimer’s disease is a bastard without a cure. It’s the sixth leading cause of death in America per the Center for Disease Control, and according to the Alzheimer’s Association, 1 in 9 American adults over 65 has it. However, there may be a ray of hope ahead for sufferers and their families. According to observational […]

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Positive results from two phase 1b studies of ALZ-801 (Alzheon Inc.) have provided the clinical data necessary to move ALZ-801 into a pivotal phase 3 program in patients with Alzheimer’s disease (AD) who are homozygous for the epsilon-4 allele of the apolipoprotein E gene (APOE4/4). ALZ-801 is an “optimized” prodrug of tramiprosate. In 2009, tramiprosate […]

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Public health officials have identified the first reported occurrence of female-to-male sexual transmission of Zika virus, according to the Centers for Disease Control and Prevention (CDC). A routine investigation by the New York City Department of Health and Mental Hygiene (DOHMH) identified a nonpregnant woman in her 20s who reported she had engaged in a […]

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LOS ANGELES–(BUSINESS WIRE)– Phytecs is expanding its preclinical research program on its novel fluorinated cannabidiol, HUF-101, along with its family of related drug molecules developed by noted medicinal chemist and Phytecs Director of Global Research, Prof. Raphael Mechoulam of The Hebrew University of Jerusalem. A new preclinical study found HUF-101 effective in mice models predictive […]

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LOS ANGELES–(BUSINESS WIRE)–Phytecs is expanding its preclinical research program on its novel fluorinated cannabidiol, HUF-101, along with its family of related drug molecules developed by noted medicinal chemist and Phytecs Director of Global Research, Prof. Raphael Mechoulam of The Hebrew University of Jerusalem. A new preclinical study found HUF-101 effective in mice models predictive of […]

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LOS ANGELES–(BUSINESS WIRE)–Phytecs is expanding its preclinical research program on its novel fluorinated cannabidiol, HUF-101, along with its family of related drug molecules developed by noted medicinal chemist and Phytecs Director of Global Research, Prof. Raphael Mechoulam of The Hebrew University of Jerusalem. A new preclinical study found HUF-101 effective in mice models predictive of […]

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Breast cancer metastasized to the liver. Credit: Courtesy of National Cancer Institute UC Berkeley researchers have found a long-elusive Achilles’ heel within “triple-negative” breast tumors, a common type of breast cancer that is difficult to treat. The scientists then used a drug-like molecule to successfully target this vulnerability, killing cancer cells in the lab and […]

IMAGE: Mastomys coucha rodents vaccinated against skin papillomavirus (MnPV) do not develop skin tumors, in contrast to unvaccinated animals. view more Credit: Daniel Hasche Papillomaviruses (linked to cervical cancer when they infect the mucosal tissue in the female reproductive tract) can also infect normal skin, where they cause warts and possibly non-melanoma skin cancer, mostly in […]