Bladder disturbances are common in people with MS and usually consist of urgency, frequency, incomplete emptying of the bladder, and, sometimes, incontinence. A urinary tract infection may explain some of these bladder issues, and should always be ruled out before starting any medication for ongoing bladder problems in multiple sclerosis.
Detrol (tolterodine) is an FDA-approved prescription medicine for the treatment of overactive bladder (leaks, urgency and going too often). It is often prescribed to MS patients struggling with bladder issues.
Tolterodine is an antimuscarinic medicine. Antimuscarinic drugs reduce involuntary contractions of the bladder muscles and increase bladder capacity. Tolterodine works by relaxing the bladder muscles and preventing contractions.
The most common side effects are dry mouth, constipation, headache, and stomach pain.
Tolterodine may cause serious allergic reactions. Symptoms of a serious allergic reaction may include swelling of the face, lips, throat, or tongue.
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