GW Pharmaceuticals‘ Epidiolex, the first plant-derived cannabidiol (CBD) medication to be approved by the U.S. Food and Drug Administration (FDA), reduces the frequency of epileptic seizures when used as an add-on therapy in children with Dravet syndrome, a Phase 3 clinical trial shows.
That finding was presented in a poster titled, “Cannabidiol (CBD) Significantly Reduces Convulsive Seizure Frequency in Children and Adolescents with Dravet Syndrome: Results of a Dose-ranging, Multi-center, Randomized, Placebo-controlled Trial (GWPCARE2),” at the American Academy of Neurology (AAN) Annual Meeting in Philadelphia.
Dravet syndrome is a rare genetic disorder characterized by severe, recurrent seizures that fail to respond to treatment with conventional anti-epileptic drugs.
Marketed by Greenwich Biosciences, a subsidiary of GW Pharmaceuticals, Epidiolex is a purified liquid formulation of plant-derived cannabis that is supplied as a 100 mg/mL strawberry-flavored oral solution in a sesame oil base.
Previous clinical trials