Kalytera Terminates Pre-Clinical Programs In Bone Disease

Kalytera Therapeutics will terminate its pre-clinical development programs in the treatment of bone disease. The company has determined that additional investments of time and resources in these programs are not appropriate given the other opportunities in its product development pipeline.

The terminated programs were evaluating three synthetic endocannabinoid compounds, KAL436, KAL439 and KAL671, in bone fracture healing, and osteogenesis imperfecta and osteoporosis. In connection with the termination of these programs, Kalytera has terminated its License Agreement with Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (“Yissum”), under which Kalytera had licensed rights to KAL436, KAL439 and KAL671.

“The decision to terminate these programs is part of our overall strategy to focus on the development of cannabinoid therapeutics, rather than synthetic endocannabinoid compounds,” stated Robert Farrell, President and CEO of Kalytera. “We will now accelerate and expand our programs evaluating cannabidiol (“CBD”) in prevention and treatment of graft versus host disease

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