Trio of previously ineffective antibiotics kills staph infections

ST. LOUIS, Sept. 14 (UPI) — A combination of 3 antibiotics was found in a study to kill methicillin-resistant Staphylococcus aureus, or MRSA, in all mice that were treated with it.

The research team has been working with antibiotics that are ineffective against specific pathogens that have evolved to resist them. The three drugs they tested against MRSA — meropenem, piperacillin and tazobactam — are members of a group of antibiotic called beta-lactams that have not had an effect against MRSA in decades.

When combined, the researchers reported it was as effective as one of the strongest drugs available to treat the pathogen.

“This three-drug combination appears to prevent MRSA from becoming resistant to it,” said Dr. Gautam Dantas, an associate professor of pathology and immunology, in a press release. “We know all bacteria eventually develop resistance to antibiotics, but this trio buys us some time, potentially a significant

... read more at: